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198 Several pathways have been implicated in micropinocytosis events, such as the ERK/MAPK pathway activated by oncogenic RAS, and PI3K/mTOR signalling pathways

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Heightened ENS activity during exercise may amplify or attenuate these signals depending on microbial composition and metabolite availability, offering a plausible explanation for inter-individual variability in perceived exertion and performance that cannot be accounted for by muscle-intrinsic factors alone