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Description

1422-C IMPACT OF LONG-TERM TREATMENT WITH CONTINUOUS TENOFOVIR ALAFENAMIDE (TAF) OR AFTER SWITCH FROM TENOFOVIR DISOPROXIL FUMARATE (TDF) ON HEPATOCELLULAR CARCINOMA (HCC) INCIDENCE IN PATIENTS WITH CHRONIC HEPATITIS B (CHB) Young-Suk Lim 1 , Grace Lai-Hung C Wong 2 , Sang Hoon Ahn 3 , Wai-Kay Seto 4 , Kosh Agarwal 5 , Harry L

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Early increases in the HIF-1 target phosphoglucomutase 1 (PGM1) in seal cells may regulate glucose metabolism during hypoxia, consistent with glycolytic repression via ZBTB7A transcriptional control [73, 74]

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According to the Kaiser Family Foundation, 19 states have already had pre-release coverage waivers approved, and another nine states have pending waivers

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Moreover, it promotes degeneration of epithelial cells of the proximal convoluted tubule and tubular cylinders, enhances focal mineralization, damages podocytes of the Bowman's capsule, increases serum levels of urea and creatinine, and brings about histological changes in kidney tubules ( Figure 4 ) [77,84]

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