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The Collateral Damage: Allopregnanolone Allopregnanolone (ALLO) is synthesized in the brain from progesterone via a two-step pathway: Progesterone 5-dihydroprogesterone (via 5-alpha reductase) 5-DHP Allopregnanolone (via 3-HSD) Because 5-AR is the rate-limiting step, inhibiting it blocks ALLO productioneven when progesterone levels are adequate

Use it on its own or layered after your favorite serum for a glowing, youthful complexion

This is one of the most common points of confusion for new patients, and its also why some people give up too early

The importance of mitAspAT as a cysteine S -conjugate -lyase in the bioactivation of TFEC is underscored by the work of Bruschi et al