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On the other hand, the safe dose level of intravenously administered sodium selenite, defined as maximum tolerated dose (MTD), was reported to be 10.2 mgm 2 in terminal cancer patients and implied the importance of kidney function in the excretion of Se from selenite since the pharmacokinetic results demonstrated a linear increase in plasma Se concentration with respect to total Se dose [440]

Harvell DM, Strecker TE, Xie B, Pennington KL, McComb RD, Shull JD: Dietary energy restriction inhibits estrogen-induced mammary, but not pituitary, tumorigenesis in the ACI rat

Figure 3 3.4 Subcellular localization of NbCu/Zn-SOD-1 in Nicotiana benthamiana To determine the subcellular localization of NbCu/Zn-SOD-1 in plant cells, we cloned the NbCu/Zn-SOD-1 sequence into the recombinant vector 1,300-GFP-EV

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