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doi: 10.3389/focsu.2025.1575728 Received 12 February 2025 Accepted 18 March 2025 Published 04 April 2025 Volume 3 - 2025 Edited by Vinicius Tavares Kutter, Federal University of Par, Brazil Reviewed by Baoxiao Qu, Chinese Academy of Sciences (CAS), China Mller L., Federal University of Rio Grande, Brazil Updates Copyright 2025 Alves, Gusso-Choueri, Altafim, Ferraz, Trevizani, Felix, Figueira, Abessa and Choueri

On the other hand, T cell-depleted animals showed higher viral RNA load in comparison to immunized mice that received the isotype control (KLH) and similar load to non-immunized animals (pCTV) (Fig