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10.1124/jpet.116.233627 J

In contrast to BMAL1 expression in the lens, CLOCK expression did not fluctuate over the 24-hour period ( Figure 3B ) and the subcellular localisation of CLOCK remained nuclear during the light vs dark period ( Figures 5EH, EH )

Eukaryotes lack this capacity and in particular complex animals can excrete absorbed Mercury only with difficulty, therefore most of the dose accumulates over time in long-half-life forms, from which the metal can be released and reach biochemically-impairing levels and thus exert toxic effects