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Over three decades ago, John Bienenstock proposed the concept of a common mucosal immune system, suggesting that the mucosal immune system itself is an organ where mucosal immune cells distributed throughout the body can interact across different mucosal tissues and organs 55

This is particularly useful when monitoring a lumps changes over weeks or when seeking a second opinion without delay

The pathological changes could also include altered brain metabolism, excitotoxicity, free radical generation, neuroinflammation, blood-brain barrier dysfunction, and apoptosis

Effectiveness of an early supplementation scheme of high-dose vitamin a versus standard WHO protocol in Gambian mothers and infants: a randomised controlled trial