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The need of the hour is to have more randomized, double-blind, placebo-controlled trials with a larger sample size, long term follow-up period, with well defined primary and secondary outcomes, targeted to evaluate the efficacy and safety of the skin-lightening effects of topical, oral and parenteral glutathione

The literature reviewed underscores the importance of daily intake of B complex vitamins to maintain normal serum levels and optimal neuronal function

As the glutathione levels fade, so do the effects

While more extensive studies are required to understand this association better, this study highlights the potential association between peripheral trauma and CBS [ 20 ]