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Organoid modeling of the tumor immune microenvironment

Mechanistically, these effects appeared to be mediated through mitochondrial uncoupling, AMPK activation, modulation of mTOR and PPAR signaling, improved mitochondrial bioenergetics, antioxidant defense and global metabolic reprogramming (Fig

Although its indication is for the treatment of iron deficiency in patients with renal failure, it is also clinically used for MRI of adrenal glands and kidneys [183,184]