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Description

Activated Parkin ubiquitinates various OMM proteins, which are subsequently phosphorylated by PINK1 to form phospho-ubiquitin chains that recruit autophagy receptors to induce mitophagy (52)

Reiners JJ Jr, Herlick S

doi: 10.1111/ijcp.14618

Targeting glycolysis Glycolysis has emerged as a pivotal therapeutic target in cardiovascular diseases, serving as a critical energy source for cardiomyocytes adapting to hypoxic conditions