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Description

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy

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Under continuous stimulation of IGF-1, IGF-1R/MAPK/PI3K signaling is activated, leading to resistance to estrogen tamoxifen and fluvestrant

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Nevertheless, the experiment would be stopped if two DLTs happen at the initial 800 mg dosage level

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Zhu L, Dai LM, Shen H, Gu PQ, Zheng K, Liu YJ, et al

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