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In addition, the SMILES of several known inhibitors of GPx1 previously confirmed to have GPx1 inhibitory activity were obtained from the literature to represent positive controls for the in silico analysis and added to the larger database (see Table I)

All of these tests are actually general markers

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Body weights were recorded weekly, and no significant differences were observed between control or Ucp1-Cre-Scly KO mice of either sex on chow (Fig