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Glutamate-cysteine ligase (GCL) catalyzes the formation of -glutamylcysteine (gGC) from glutamic acid (Glu) and Cys, followed by glutathione synthetase adding glycine (Gly) to form GSH [19,20,21]

doi: 10.1093/advances/nmab106 85

31 All these factors stimulate p53 activity and lead to cellular apoptosis in ischemic stroke

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