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RoerinkMEvan der SchaafMEDinarelloCAKnoopHvan der MeerJWM

The PI3K/Akt-Nrf2 signaling pathway and mitophagy synergistically mediate hydroxytyrosol to alleviate intestinal oxidative damage

administration of graded doses of indole (2.5 - 10.0 mg/kg) or L-tryptophan (50 - 200 mg/kg)

Additionally, the challenge of this study is that in vivo and in vitro models may not fully reproduce the diseases complex and dynamic character as it occurs in the human body