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27 An increased oxidative burden occurs in the lungs of patients with COPD, and oxidative stress may be involved in various the pathogenic processes, such as direct injury to lung cells, mucus hypersecretion, inactivation of antiproteases and enhancing lung inflammation through activation of redox-sensitive transcription factors

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Other Lab Methods Membrane filtration pushes a measured volume of water through a fine filter that traps bacteria, which are then grown on a culture medium and counted, a method well suited to samples with few organisms

Manganese peptide complexes (e.g., manganese tripeptide-1) have been explored as alternatives that avoid copper-related skin discoloration concerns while providing metal-dependent enzymatic activation