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Vitamin C, for instance, is most stable and bioavailable at a pH below 3.5

To improve vitamin B12 status, consume more from your diet (such as from meat, fish, eggs, liver and cheese), and consider supplementing, especially if you dont eat animal products

Furthermore, mechanistic studies investigating the GSH-susceptibility of succinimide thioether bonds found the type of thiol and N -substituent used to play key roles in the rate of cleavage of succinimide thioether linkages in reducing environments, where N -substituents capable of forming more hydrogen bonds and thiol groups of low pKas led to greater rates of bond cleavage in GSH [48]

1A and B, Table S2)