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doi: 10.1056/NEJMoa1609214 77 BernerFBomzeDDiemSAliOHFasslerMRingSet al

Keynote SSRP FOUNDER William Seeds, MD SSRP FACULTY Carl Paige, MD SSRP FACULTY Siobhan Newman, MD SSRP FACULTY William Christian Haas III, MD, MBA SSRP FACULTY Stephen Matta, DO, MBA, FSSRP SSRP FACULTY Jamie Gabel, PA-C SSRP FACULTY Valerie Donaldson, MD SSRP FACULTY Khanh Nguyen, MD Devaki Lindsey Berkson, MA, DC, DACBN, CNS SSRP FELLOW Tammy Wolf, RN CANS FNP-S SSRP MEMBER Kelli Musa, FMP Sharon Hausman-Cohen, MD, FAAFP, ABOIM Maksim Chmerkovskiy Peta Murgatroyd SSRP MEMBER Lea Llovio, CWL Sal Di Stefano, CO-FOUNDER MIND PUMP MEDIA, CPT, AUTHOR Omar Rahman, MD, MBA SSRP MEMBER Lauren Fitzgerald, M.D

Briefly, Mercury(II) ions present in the environment cross the microorganisms cellular membrane and are scavenged by MerA, a homo-dimeric enzyme which sandwiches the Hg 2+ between a pair of catalytically essential cysteine thiol groups, to make a protein-embedded mercury(II)-bis-thiolate

Keep vitamin C supplementation down to 1-2 grams daily or use 10mg of B6 per gram of vitamin C if you choose to supplement higher