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Although the mechanisms of smoking-induced susceptibility to higher risk of CRC remain to be elucidated, preliminary evidence suggests a collective role of host, microbial, and smoking, such as intestinal and immune disruption, impaired clearance of pathogens, changes in the virulence of bacteria and fungi, and ingestion of bacteria that are present in cigarettes [171]

Observer reached out to the author of the AJR article for comment but did not immediately receive a response

That was a very strange request, Smith said, but I looked up the matter and found that I had power to do so. He then called his wife, Mary, and asked her to come down to the store and bring their copy of the Episcopal Prayer Book with her

NOTE: Pipes not included