glutathione peroxidase hydrogen peroxide The role of peroxidase-1 in health and disease Superoxide Production during Ischemia and

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Animal experiments confirmed that dural injection of bone marrow mesenchymal stem cell-derived exosomes miR-367-3p significantly reduced the expression of EZH2 in spinal cord tissues of EAE mice, increased the expression of SLC7A11, GPX4, GSH, and SOD, decreased the levels of Fe 2+ and MDA, inhibited spinal cord iron deposition, ferroptosis, and inflammation, and alleviated spinal cord injury ( 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue

ROS can directly interact with the subunit of PI3K, enhancing its activity and promoting the conversion of PIP2 to PIP3 (92)

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