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The MAPK family includes three major subgroups, extracellular signal regulated kinase (ERK), p38 MAPK (p38), and c-Jun N-terminal kinase/stress activated protein kinase (JNK)

Then, mice were administered intraperitoneally with 2 mg/kg of GSTP (WT), or sterile saline, respectively, 30 min after CLP surgery

show the impact of reduced function of histone methyltransferase, such as NSD1 and NSD2, accountable for catalyzing the dimethylation of lysine 36 on histone H3 (H3K36me2) in HNSCC cells [128]