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From a nanotherapeutic perspective, these processes are especially important because they define opportunities for antioxidant, mitochondria-targeted, and lysosome-restoring nanomedicines

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doi: 10.1038/s41371-019-0273-0

Fluorescence staining revealed that oocytes from young mice displayed barrel-shaped spindles with properly aligned chromosomes, whereas oocytes from aged mice exhibited disordered spindles and misaligned chromosomes (Fig