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SKU: 40218189674
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What Is a Herxheimer Reaction

Accumulation of free radicals and increased pro-inflammatory cytokines such as IL-1 and IL-6, combined with decreased expression of anti-inflammatory cytokines such as IL-10 and IL-4, contribute to the maintenance of the senescent inflammatory state (Ye and Johnson, 2001

S., MacMore, J

In aged humans (5080-years-old), microglia in the white matter have increased expression of genes associated with lipid-metabolism as well [e.g., secreted phosphoprotein 1 (SPP1) and apolipoprotein E (APOE)], hinting at the possibility of the presence of WAMs in humans