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PMID: 25157774

Trigger points here cause neck stiffness, shoulder pain, and frequently refer pain into the head

The lower K D value determined from competition with His might arise due to the omitting of the formation of a putative ternary complex between HSA, Cu(II) ion and His in the binding scheme, which should result in higher affinity estimates, since the copper in the ternary complex is found in the HMW peak