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10.1038/nature24297 64

Mitochondrial dysfunction Imbalance of oxidation and antioxidation Mitochondrial ROS produced through the respiratory chain is the major source of ROS (Fig

The cluster analysis was performed with the Genesis software ( Volcano plots were generated with GraphPad Prism 8 software or in Python using Seaborn and Matplotlib packages for genes with normalized reads, with -log 10 adj p -values on the y -axis and log 2 FC values on the x -axis