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Procarbazine, lomustine and vincristine for recurrent high-grade glioma

Additionally, the promoter features an antioxidant response element (ARE) and metal response element (MRE) within the first 160 bp of the transcription start point, which respond to oxidative stimuli such as H 2 O 2 and tert-butylhydroquinone [35]

The second, third, and fourth group received an oral dose of Sildenafil (1.48 mg/kg), Tadalafil (0.285 mg/kg), and Vardenafil (0.285 mg/kg) respectively, three times per week for 12 weeks