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It is worth considering that, although the present work focused on a subset of CpN sites within the mtDNA regions of mitochondrial promotor region (D-loop) and two mitochondrial protein coding genes ( MT-CYB and MT-CO2 ), LC-MS/MS analyses also showed no differential methylation induced by long-term CSE exposure

Note: Find out in advance about permitted tobacco quantities or the general legal situation for smokables when travelling abroad

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We also identified relevant research gaps, which will guide future researchers to conduct rigorously designed human studies and meta-analysis examining risk of cancer from e-cigarette use