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Prenatal development of lung antioxidant enzymes in four species

155 It is characterized by abnormal extracellular amyloid-beta (A) aggregates, which form diffuse and neuritic plaques, as well as hyperphosphorylated tau aggregates, which form intraneuronal neurofibrillary tangles

Nanodelivery of BA receptor modulatorssuch as the FXR agonist obeticholic acid (OCA) and the GPBAR1 antagonist 5-cholanic acid (5-CA)enhanced NK, NKT, and CD8+ T cell infiltration and triggered potent anti-tumor responses in liver cancer models (152)

Higher steroid dosing in the placebo arm may have contributed to the relatively high response rates, confounding the primary efficacy outcome