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Peer review Peer review information Nature Metabolism thanks Xun Huang and the other, anonymous, reviewer for their contribution to the peer review of this work

Instead, they found just the levels of both that they expected

This study suggests that, in the context of p53 deficiency, SLC7A11 can promote tumor development through a non-canonical mechanism by directly interacting with ALOX12 and inhibiting ALOX12-mediated ferroptosis, which seems to be independent of its cystine transporting activity (Fig