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Description

Cancers 11(5):678

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Specifically, Fe 2+ overload activates the protein kinase B (AKT)/mechanistic target of rapamycin complex 1 (mTORC1) pathway, while also inhibiting the expression of transcription factor EB (TFEB), a master transcriptional regulator of autophagosome-lysosome fusion

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During sleep, this pressure is ameliorated by removing scavenging free radicals with antioxidant enzymes which can be regulated with sleepwake modulators like melatonin

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While most individuals recover from post-concussion syndrome with time and appropriate treatment, some may experience persistent symptoms that can last for years

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