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350 Mitochondrial dysfunction in Schwann cells triggers alterations in lipid metabolism, leading to myelin sheath dysfunction and accumulation of toxic lipid intermediates, which cause axonal degeneration and neuropathy

These typically disappear as the body adjusts

Both Leqembi and another drug expected to be approved this year, Eli Lillys donanemab, work by clearing the amyloid plaque buildups in the brain associated with Alzheimers disease