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Instead, these organs employ an amino acid transporter to absorb glycine, cysteine, and glutamate for intracellular de novo GSH synthesis

Originally published on Space.com

The discontinuous and fenestrated endothelium in rapidly growing malignant tumors and the poor lymphatic system allow LNPs and internalized siRNAs greater accumulation and slower clearance in solid tumors, referred to as the enhanced permeation and retention (EPR) effect