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Co-incubation with MK-7, and to a similar extent vitamin K1 (Figure S4A S4B), blunted these phenotypic shifts: Mesenchymal protein induction fell (Figure S3B S3E) while endothelial marker proteins were restored (Figure S3F S3J)

doi: 10.1038/s41392-021-00827-6 88 NgoBKimEOsorio-VasquezVDollSBustraanSLiangRJet al

The aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts

A previous small-sample study showed that pemoline has a certain effect on relieving symptoms related to depression, such as disturbances in concentration, memory, tension and fatigue in depressed patients, but there is a lack of evidence from large-sample randomized controlled studies (86)