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This view must be regarded as superseded by the hypothesis that the disease is based on a hereditary autoimmunity of two types, one consisting in the total penetrance of an autosomal dominant gene probably related to the HLA (histocompatibility) locus of chromosome 6 (rare form - 1 case out of 4 - which is inherited from father to son) and the other in partial penetrance (more frequent) in which a predisposition to fibrosclerosing autoimmune diseases is inherited (Belgrano E., ibid

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Therefore, it can be postulated that treatment of human chronic wounds with glutathione both systemically and locally after debridement can be effective in resolving chronicity.[] ANTIVIRAL ROLE Although yet not fully elucidated, the role of glutathione as an antiviral has been studied