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The genetic material of these microbes, the gut microbiome, consists of more than 45 million non-redundant genes, when only the oral and gastrointestinal microbiome is considered [3], and provides for a number of functions that integrate and complement that of the human genome

Accordingly , researchers rely on these standardized resources when designing experiments and validating laboratory findings

In the simplest caseand the most useful in designing drug dosage regimensthe body may be considered as a single compartment (as illustrated in Figure 32 B) of a size equal to the volume of distribution (V)

& Elbaum-Garfinkle, S