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It protects our body from oxidative damage and has anti-aging and anti-inflammatory properties

To purify RNA, samples were processed with PureLink RNA Mini Kit (Invitrogen, 12183025) according to the manufacturers instructions, and the RNA concentration and quality were checked with a spectrophotometer (Thermo Scientific, NanoDrop 2000)

10.1136/bmjdrc-2020-001426 117 YangW

Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility