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doi: 10.1016/j.mad.2015.01.003

This approach can help maximize the antioxidant benefits and improve the overall effectiveness of supplementation

To determine the effects of stimulating TCA cycle activity, we treated hepatocytes with dichloroacetate (DCA), which stimulates substrate entry into the TCA cycle by inhibiting PDKs (Constantin-Teodosiu et al., 1999, Wu et al., 2018)