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Therefore, targeting NADPH-regulated release of ROS and ferroptosis may be a novel therapeutic strategy to treat DN [243]

Coenzyme A synthesis from pantothenic acid The figure illustrates the biochemical pathway that converts pantothenic acid (pantothenate) into coenzyme A, showing chemical structures of intermediates and the enzymes involved

In particular, pulmonary embolism caused by DVT is the main cause of maternal death 3,4

33 Previously, our group has reported an angiopep-2 (a dual-targeting ligand towards LRP-1) modified nanogel for targeted delivery of anti-epileptic drugs