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Through passive targeting, these ligand-modified nanoparticles can gather in the tumor and then transit into tumor cells via active targeting, causing more specific and improved therapeutic effects

Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice

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167,168,169 Unlike other nucleic acid-based drugs, aptamers specifically recognize and bind target molecules, such as peptides, proteins, viruses, bacteria, and cells, relying on their unique three-dimensional conformation