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Any mention of retatrutide on this website is provided for educational purposes only

[DOI] [PMC free article] [PubMed] [Google Scholar] 117c

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Further study based on an artificial model of GPX4 deletion in the proximal tubules indicated that knockout of GPX4 caused cell death in a pathologically relevant form of ferroptosis and spontaneous tubular necrosis, and the inhibition of ferroptosis by liproxstatin-1 was able to mitigate ischemia/reperfusion-induced tissue damage [85]