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This mechanism ensures that bioactive compoundssuch as vitamins, polyphenols, and antioxidantsare absorbed where they are most needed, leading to faster and more consistent physiological responses

However, stabilized R-ALA still lacks the volume of long-term clinical research supporting racemic ALA

The human gut microbiome is fed by dietary nutrition to generate bile acids, SCFAs and other bioactive compounds, which are necessary for maintaining host physiology involving in protein metabolism, glucose metabolism and lipid metabolism (94)

Proteomic analysis revealed that P300 was the only histone acetyltransferase (HAT) family member downregulated in granulosa cells following DON treatment, suggesting that P300 plays a predominant role in regulating lactylation in porcine granulosa cells (Fig