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*Correspondence: Yan Yuan, [email protected] This article was submitted to Virology, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Irreversible Inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

This is of particular interest when the target protein lacks classical druggable pocketsi , in which V d and V a represent the volumes of the donor and the acceptor wells, respectively, A is the surface of the artificial membrane, t is the permeation time, whilst d a and d eq are the absorbance measured in the acceptor well and the theoretical equilibrium absorbance value, respectively

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