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& Kalantar, H

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The major contributor of superoxide radicals (O 2 ) is NADPH oxidase, which is synthesized during cellular respiration by reducing one-electron oxygen molecules with electrons delivered by NADPH

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Furthermore, chemical and physical interactions between EXOs and the hydrogel matrix can influence exosome release and therapeutic effectiveness (Ghahremani-Nasab et al., 2025)

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