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For example, the study conducted by Mesquita et al

mRNA-4157, a lipid-encapsulated personalized vaccine that encodes various neoantigens identified through a proprietary algorithm, was assessed as adjuvant monotherapy in patients with resected solid tumors (including melanoma, bladder carcinoma, HPV-negative HNSCC, NSCLC, SCLC, MSI-High, or TMB-High cancers) and in conjunction with pembrolizumab in patients with advanced or metastatic disease

In our collective, 50% of patients had a preoperative BMI value lower than 30 kg/m 2 , and BMI and body fat steadily decreased during the observation period although patients reported normal food intake throughout the follow-up period

GenBank AA308926 EST179848 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end similar to translation elongation factor 1, alpha, mRNA sequence