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Future studies should leverage various techniques, including omics, imaging, and animal models, to investigate the molecular mechanisms of ionizing radiation-induced ferroptosis in the lens and clarify the role of ferroptosis at different stages of radiation-induced cataract development

Abstract Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show negative effects on tumor formation, necessitating characterization of the causal associations between antioxidants and cancer risk

Idebenone ameliorates rotenone-induced Parkinsons disease in rats through decreasing lipid peroxidation

Damaged lysosomes undergo selective autophagy The hallmark for many forms of selective organelle autophagy is surface ubiquitination